Cheap Flights from Panama City to Medellin starting at RM 423

We've found these cheap flights for you. You can book one-way or return flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Cheapest time to fly from Panama City to Medellin

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights

From price

23 30
Apr

30 6
6 13
13 20
20 27
May

27 4
4 11
11 18
18 25
Jun

25 1
1 8
8 15

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

When are flight tickets from Panama City (PTY) to Medellin (MDE) the cheapest?

Airlines adjust prices for flights from Panama City to Medellin based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Panama City (PTY) to Medellin (MDE) cost?

According to Trip.com's data, the lowest price is around RM 1,218.
How long does it take to fly from Panama City (PTY) to Medellin (MDE)?

It takes about 1 hour 22 minutes to fly from Panama City (PTY) to Medellin (MDE).
What is the transportation method from the main airport to downtown in Medellin?
- The distance from Jose Marie Cordova Airport to downtown is about 17km, by taxi about 30 minutes.
- The distance from Olaya Herrera Airport to downtown is about 2km, by taxi about 20 minutes.
What time does the earliest flight from Panama City to Medellin depart?

The earliest flight departs from Panama City (PTY) at 07:01 and arrives in Medellin (MDE) at 08:26.
What time does the latest flight from Panama City to Medellin depart?

The latest flight departs from Panama City (PTY) at 21:27 and arrives in Medellin (MDE) at 22:52.
What are the most popular airlines that fly from Panama City (PTY) to Medellin (MDE)?

Airlines with flights from Panama City (PTY) to Medellin (MDE): Copa Airlines, KLM, avianca, United Airlines and Turkish Airlines.
What's the most popular airline for non-stop flights from Panama City (PTY) to Medellin (MDE)?

Copa Airlines operates 4 direct flights from Panama City (PTY) to Medellin (MDE).
How many airports in Medellin (MDE)?

There are 2 airport(s) in Medellin (MDE): Olaya Herrera Airport and Jose Marie Cordova Airport.

How to find a cheap flight from Panama City to Medellin

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Medellin. Book your flights at the right time and save more.

Be flexible with your travel dates to get the cheapest flight from Panama City to Medellin.

Simply tap "Date" on the flight search bar to browse through the calendar and check out airfare from Panama City to Medellin over the next 6 months in 2025. If you're planning to fly within the next three months, it looks like the most affordable option is on Thu, Mar 27, with one-way flights priced at just RM 423.

Compare cheap flight deals from Panama City to Medellin across hundreds of airlines.

With our extensive search, you can compare prices from over 500 airlines to find the cheapest flight tickets from Panama City to Medellin. The cheapest airline for this route is avianca.

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Don't miss out on cheap flight deals and promo codes from Panama City to Medellin.

You can always find the latest offers through Trip.com Deals and Promo Codes for cheap flights. By signing up for a free membership, you'll get access to even more deals for your flights.

Book early or wait until the last minute.

It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.

Search for flights on the go.

For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from Panama City to Medellin and snag some exclusive deals just for you.

Flight Information from Panama City to Medellin

Cheapest direct flight price	RM 422
Cheapest return ticket price	RM 897
Off-season for travel	February
Peak season for travel	June
Flight distance	530.92km
Average flight time	1 hour 22 minutes
Popular airline	avianca